JOURNAL OF BIOMOLECULAR SCREENING

Advancing Life Sciences R&D: SLAS Discovery reports how scientists develop and utilize novel technologies and/or approaches to provide and characterize chemical and biological tools to understand and treat human disease.SLAS Discovery is a peer-reviewed journal that publishes scientific reports that enable and improve target validation, evaluate current drug discovery technologies, provide novel research tools, and incorporate research approaches that enhance depth of knowledge and drug discovery success.SLAS Discovery emphasizes scientific and technical advances in target identification/validation (including chemical probes, RNA silencing, gene editing technologies); biomarker discovery; assay development; virtual, medium- or high-throughput screening (biochemical and biological, biophysical, phenotypic, toxicological, ADME); lead generation/optimization; chemical biology; and informatics (data analysis, image analysis, statistics, bio- and chemo-informatics). Review articles on target biology, new paradigms in drug discovery and advances in drug discovery technologies.SLAS Discovery is of particular interest to those involved in analytical chemistry, applied microbiology, automation, biochemistry, bioengineering, biomedical optics, biotechnology, bioinformatics, cell biology, DNA science and technology, genetics, information technology, medicinal chemistry, molecular biology, natural products chemistry, organic chemistry, pharmacology, spectroscopy, and toxicology.SLAS Discovery is a member of the Committee on Publication Ethics (COPE) and was published previously (1996-2016) as the Journal of Biomolecular Screening (JBS).

JOURNAL OF BIOMOLECULAR SCREENING期刊中文简介

推进生命科学研发：SLAS发现报告了科学家如何开发和利用新技术和/或方法来提供和描述理解和治疗人类疾病的化学和生物工具。SLAS Discovery是一个同行评审的期刊，它发布科学报告，以实现和改进目标验证，评估当前的药物发现技术，提供新颖的研究工具，并结合研究方法，提高知识深度和药物发现的成功率。SLAS发现强调了目标识别/验证（包括化学探针、RNA沉默、基因编辑技术）的科学和技术进步；生物标志物发现；分析开发；虚拟、中或高通量筛选（生化和生物、生物物理、表型、毒理学、ADME）；铅生成/光学数字化；化学生物学；信息学（数据分析、图像分析、统计学、生物和化学信息学）。综述目标生物学、药物发现的新范式和药物发现技术的进展。SLAS的发现对分析化学、应用微生物学、自动化、生物化学、生物工程、生物医学光学、生物技术、生物信息学、细胞生物学、DNA科学与技术、遗传学、信息技术、医学化学、分子生物学、天然产物化学、有机物等领域的研究者特别感兴趣。化学、药理学、光谱学和毒理学。SLAS Discovery是出版伦理委员会（COPE）的成员，之前（1996-2016年）作为生物分子筛选杂志（JBS）出版。